Tiomolibdate diammonium ( Ammonium molybdenum sulfide | Ammonium tetrathiomolybdate | ATTM | Coprexa | NSC 286644 )

产品货号. M27125 CAS No. 15060-55-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Tiomolibdate diammonium
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Tiomolibdate diammium 是一种超氧化物歧化酶 1 (SOD1) 抑制剂，具有抗血管生成和抗肿瘤活性。
产品描述

Tiomolibdate diammonium is an inhibitor of superoxide dismutase 1 (SOD1) exerting antiangiogenic and antitumor activities. Tiomolibdate diammonium inhibits the activities of cuproenzymes, including SOD1 and COX.
体外实验

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体内实验

Ammonium tetrathiomolybdate(VI) (ATTM) (i.v.; 10?mg/kg) confers significant neuroprotection. Animal Model:Wistar Rats Dosage:10?mg/kg Administration:Intravenous Result:Showed improved functional activity at both 24 h and 7-days post-reperfusion, in parallel with a significant reduction in infarct size.
同义词

Ammonium molybdenum sulfide | Ammonium tetrathiomolybdate | ATTM | Coprexa | NSC 286644
通路

Others
靶点

Other Targets
受体

Apoptosis| ERK1| ERK2
研究领域

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适应症

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1.Hanna Piotrowska, et al. DMU-212 inhibits tumor growth in xenograft model of human ovarian cancer. Biomed Pharmacother. 2014 May;68(4):397-400.

计算器

产品手册

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